Determination of viral titer and host cell proteins to support viral vector production in gene therapy using an automated, miniaturized immunoassay
The rapid development of gene therapy treatments has led to a great demand for assays with quick turnaround times to
support optimization of the production of viral vectors including those based on rAAV (recombinant adeno-associated
virus) and the lentiviruses, HIV-1 (human immunodeficiency virus 1) and EIA (equine infectious anemia).
Here we report the performance of three assays run on Gyrolab® system that can be used to monitor the preparation
and purity of viral vectors:
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