Rapid in-solution equilibrium approach to KD determination of biotherapeutic drug candidates
Johan Engström, senior scientist at Gyros Protein Technologies, presents aspects of in-solution equilibrium affinity experiments using Gyrolab™ systems. Examples of determinations of picomolar affinities for several marketed TNFα antagonists will be discussed.
Introduction to setting up and evaluating classical in-solution equilibrium experiments for determination of sub-nanomolar KD’s and active concentrations of interactants
Benefits of listening to the webinar:
- Hear about how you can determine sub-nanomolar KD’s within an hour
- Find out how easy it is to set up in-solution equilibrium experiments using intuitive software
- Learn how the results are fitted to obtain KD values and active concentrations